A fully integrated RSSI and an ultra-low power SAR ADC for 5.8 GHz DSRC ETC transceiver

This study presents a monolithic received signal strength indicator (RSSI) and an ultra-low power SAR ADC for 5.8 GHz DSRC transceiver in China electronic toll collection systems. In order to meet the stringent requirement of wide input range for the transceiver, two RSSIs collaborate with auxiliary ADC circuits to provide the digitalized received signal strength to the digital baseband of a transceiver. The RSSI design achieves fast transient response and low power consumption with a small die area by using internal active low-pass filters instead of external passive ones. The proposed design has been fabricated using a 0.13 μm 2P6M CMOS technology. Measurement results show that the overall input dynamic range is 86 dB with an accuracy of ±1.72 dB and a transient response of less than 2 μs. Compared with the state-of-the-art designs in the literature, the overall input range and transient settling time are improved by at least 14.6%, and 300%, respectively

Stable oxygen and carbon isotopes from the planktonic foraminifera Neogloboquadrina pachyderma in the Western Arctic surface sediments: Implications for water mass distribution

Neogloboquadrina pachyderma is the most abundant planktonic foraminifera species found in the modern polar oceans. The δ18O and δ13C of N. pachyderma from the Western Arctic Ocean sediments were analyzed to reveal the implications of the proxies to environmental changes. The ±18O from N. pachyderma in the Chukchi Sea reflect the water mass distribution in this area. Heavier ±18O values were found along the Anadyr Current (AC) and lighter values in the central and eastern Chukchi Sea. These may reflect the freshwater signal from the Alaska Coastal Current (ACC) and Bering Sea Shelf Water (BSSW). The light δ18O signature in the high Arctic basin comes from the freshwater stored in the Arctic surface layer. The δ13C distribution pattern in the Chukchi Sea is also influenced by the current system. High primary productivity along the AC results in heavy δ13C. The relatively low primary productivity and the freshwater component from the BSSW and ACC may be the reason for this light δ13C signal in the central and eastern Chukchi Sea. Our data reveal the importance of well ventilated Pacific Water through the Chukchi Sea into the Arctic Ocean

Direct imaging of a zero-field target skyrmion and its polarity switch in a chiral magnetic nanodisk

A target skyrmion is a flux-closed spin texture that has two-fold degeneracy and is promising as a binary state in next generation universal memories. Although its formation in nanopatterned chiral magnets has been predicted, its observation has remained challenging. Here, we use off-axis electron holography to record images of target skyrmions in a 160-nm-diameter nanodisk of the chiral magnet FeGe. We compare experimental measurements with numerical simulations, demonstrate switching between two stable degenerate target skyrmion ground states that have opposite polarities and rotation senses and discuss the observed switching mechanism.Comment: 18 pages, 4 figure

The marine environmental evolution in the northern Norwegian Sea revealed by foraminifera during the last 60 ka

Both planktonic and benthic foraminifera were identified in a sediment core collected from the northern Norwegian Sea to reconstruct the paleoceanographic evolution since the last glaciation. The assemblages and distribution patterns of dominant foraminiferal species with special habitat preferences indicated that three marine environments occurred in the northern Norwegian Sea since 62 ka BP: (1) an environment controlled by the circulation of the North Atlantic Current (NAC); (2) by polynya-related sinking of brines and upwelling of intermediate water surrounding the polynya; (3) by melt-water from Barents Sea Ice Sheet (BSIS). At 62–52.5 ka BP, a period with the highest summer insolation during the last glaciatial period, intensification of the NAC led to higher absolute abundances and higher diversity of foraminiferal faunas. The higher abundance of benthic species Cibicidoides wuellerstorfi indicates bottom water conditions that were well-ventilated with an adequate food supply; however, higher abundances of polar planktonic foraminiferal species Neogloboquadrina pachyderma (sin.) indicate that the near-surface temperatures were still low. During mid-late Marine Isotope Stage (MIS) 3 (52.5–29 ka BP), the marine environment of the northern Norwegian Sea alternately changed among the above mentioned three environments. At 29–17 ka BP during the last glacial maximum, the dominant benthic species Bolivina arctica from the Arctic Ocean indicates an extreme cold bottom environment. The BSIS expanded to its maximum extent during this period, and vast polynya formed at the edge of the ice sheet. The sinking of brines from the formation of sea ice in the polynyas caused upwelling, indicated by the upwelling adapted planktonic species Globigerinita glutinata. At 17–10 ka BP, the northern Norwegian Sea was controlled by melt-water. With the ablation of BSIS, massive amounts of melt water discharged into the Norwegian Sea, resulting in strong water column stratification, poor ventilation, and an oligotrophic bottom condition, which led to a drastic decline in the abundance and diversity of foraminifera. At 10–0 ka BP, the marine environment was transformed again by the control of the NAC, which continues to modern day. The abrupt decrease in relative abundance of Neogloboquadrina pachyderma (sin.) indicates a rise in near-surface temperature with the strengthening of the NAC and without the influence of the BSIS

A 5.8 GHz DSRC Digitally Controlled CMOS RF-SoC Transceiver for China ETC

This paper presents a 5.8 GHz dedicated short range communication (DSRC) CMOS RF-SoC transceiver with digitally controlled RF architecture for China electronic toll collection (ETC) system. The operation of key RF blocks, such as ASK modulator, power amplifier, LNA, and mixer, are directly controlled by digital baseband. Compared with state-of-the-art designs in literature, this work demonstrates remarkable advantages in design simplicity, Tx output peak power, adjacent channel power ratio (ACPR), dynamic range, occupied bandwidth (OBW), bit error rate (BER), and so on

Mn-doped CoSe2 nanosheets as high-efficiency catalysts for the oxygen evolution reaction.

In this work, we introduce for the first time an aqueous solution method followed by a selenization step to prepare Mn-doped CoSe2 nanosheets supported on nickel foam for the oxygen evolution reaction. These findings provide us highly efficient electrocatalysts instead of noble metal catalysts for the oxygen evolution reaction

Polymorphisms in thymidylate synthase gene and susceptibility to breast cancer in a Chinese population: a case-control analysis

BACKGROUND: Accumulative evidence suggests that low folate intake is associated with increased risk of breast cancer. Polymorphisms in genes involved in folate metabolism may influence DNA methylation, nucleotide synthesis, and thus individual susceptibility to cancer. Thymidylate synthase (TYMS) is a key enzyme that participates in folate metabolism and catalyzes the conversion of dUMP to dTMP in the process of DNA synthesis. Two potentially functional polymorphisms [a 28-bp tandem repeat in the TYMS 5'-untranslated enhanced region (TSER) and a 6-bp deletion/insertion in the TYMS 3'-untranslated region (TS 3'-UTR)] were suggested to be correlated with alteration of thymidylate synthase expression and associated with cancer risk. METHODS: To test the hypothesis that polymorphisms of the TYMS gene are associated with risk of breast cancer, we genotyped these two polymorphisms in a case-control study of 432 incident cases with invasive breast cancer and 473 cancer-free controls in a Chinese population. RESULTS: We found that the distribution of TS3'-UTR (1494del6) genotype frequencies were significantly different between the cases and controls (P = 0.026). Compared with the TS3'-UTR del6/del6 wild-type genotype, a significantly reduced risk was associated with the ins6/ins6 homozygous variant genotype (adjusted OR = 0.58, 95% CI = 0.35–0.97) but not the del6/ins6 genotype (OR = 1.09, 95% CI = 0.82–1.46). Furthermore, breast cancer risks associated with the TS3'-UTR del6/del6 genotype were more evident in older women, postmenopausal subjects, individuals with a younger age at first-live birth and individuals with an older age at menarche. However, there was no evidence for an association between the TSER polymorphism and breast cancer risks. CONCLUSION: These findings suggest that the TS3'-UTR del6 polymorphism may play a role in the etiology of breast cancer. Further larger population-based studies as well as functional evaluation of the variants are warranted to confirm our findings

Moisturizing and Antioxidant Effects of <i>Artemisia argyi</i> Essence Liquid in HaCaT Keratinocytes

Artemisia argyi essence liquid (AL) is an aqueous solution extracted from A. argyi using CO2 supercritical fluid extraction. There have been few investigations on the aqueous solution of A. argyi extracted via CO2 supercritical fluid extraction. This study aimed to explore the moisturizing and antioxidant effects of AL and to clarify the potential mechanism underlying those effects. Expression levels of skin moisture-related components and the H2O2-induced oxidative stress responses in human keratinocyte cells were measured via quantitative RT-qPCR, Western blot, and immunofluorescence. Our results showed that AL enhanced the expression of AQP3 and HAS2 by activating the EGFR-mediated STAT3 and MAPK signaling pathways. In addition, AL can play an antioxidant role by inhibiting the NF-κB signaling pathway and activating the Nrf2/HO-1 signaling pathway, consequently increasing the expression of antioxidant enzymes (GPX1, SOD2) and decreasing the production of reactive oxygen species (ROS). This study revealed that AL could be used as a potential moisturizing and antioxidant cosmetic ingredient